- 专利标题： Compounds and compositions for the inhibition of NAMPT
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申请号： US16538208申请日： 2019-08-12
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公开(公告)号： US10772874B2公开(公告)日： 2020-09-15
- 发明人: Kenneth W. Bair , Timm R. Baumeister , Alexandre J. Buckmelter , Karl H. Clodfelter , Peter Dragovich , Francis Gosselin , Bingsong Han , Jian Lin , Dominic J. Reynolds , Bruce Roth , Chase C. Smith , Zhongguo Wang , Po-Wai Yuen , Xiaozhang Zheng
- 申请人： Forma TM, LLC , Genentech, Inc.
- 代理机构： Choate, Hall & Stewart LLP
- 代理商 Michael A. Shinall; Erica M. D'Amato
- 主分类号： C07D491/048
- IPC分类号： C07D491/048 ; C07D487/04 ; A61K31/4355 ; A61K31/4365 ; C07D471/04 ; C07D491/04 ; C07D495/04 ; A61K31/437 ; A61K31/496 ; A61K31/497 ; A61K31/519 ; A61K31/5377 ; A61K31/55 ; A61K45/06
摘要：
The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below: