An application processing method and apparatus for an embedded universal integrated circuit card (eUICC) are disclosed. The method includes: activating, by a terminal device, an embedded universal integrated circuit card (eUICC); and selecting, by the terminal device, an Issuer Security Domain Root (ISD-R) application on the eUICC during an initialization process of the eUICC, to maintain a session between the terminal device and the eUICC. The session between the terminal device and the eUICC can be maintained during the initialization process of the eUICC.