This disclosure provides a pixel arrangement structure, a pixel structure and a production method thereof, an array substrate, and a display panel. The pixel arrangement structure comprises: a plurality of first pixel units and second pixel units which are arranged alternately in both of row direction and column direction; wherein each of the pixel units comprises nine zones forming an array of three rows by three columns, and there are first, second, and third sub-pixels, first and second retention regions, and an optional fourth sub-pixel in these zones, respectively.