Provided are systems and a method for photorealistic real-time face reenactment. An example method includes receiving a target video including a target face and a source video including a source face. The method includes determining, based on the target face, a target facial expression. The method includes determining, based on the source face, a source facial expression. The method includes synthesizing, using the parametric face model, an output face. The output face including the target face wherein the target facial expression is modified to imitate the source facial expression. The method includes generating, based on a deep neural network, mouth and eyes regions, and combining the output face, the mouth, and eyes regions to generate a frame of an output video.