A processing device receives image data of an actual condition of a patient's dental arch at an intermediate stage of a multistage orthodontic treatment plan. The processing device compares the image data of the actual condition of the patient's dental arch to a planned condition of the patient's dental arch for the intermediate stage. The processing device identifies one or more clinical signs that the actual condition of the patient's dental arch has a deviation from the planned condition of the patient's dental arch for the intermediate stage of the multi-stage orthodontic treatment plan based on a result of the comparing. The processing device determines one or more probable root causes for the deviation based on the one or more clinical signs. The processing device additionally determines one or more corrective actions for the multi-stage orthodontic treatment plan based on the one or more probable root causes.