Invention Grant
- Patent Title: Therapeutic agent for autoimmune diseases or allergy, and method for screening for the therapeutic agent
-
Application No.: US14258617Application Date: 2014-04-22
-
Publication No.: US10794907B2Publication Date: 2020-10-06
- Inventor: Atsushi Kumanogoh
- Applicant: OSAKA UNIVERSITY
- Applicant Address: JP Suita-shi
- Assignee: OSAKA UNIVERSITY
- Current Assignee: OSAKA UNIVERSITY
- Current Assignee Address: JP Suita-shi
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@5e85d899
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/566 ; C07K16/18 ; C07K16/28
Abstract:
Disclosed is a therapeutic agent for treating a cellular immune disease, comprising as an active ingredient a substance that inhibits binding between Sema3A and a Neuropilin-1/Plexin-A1 heteroreceptor. The substance includes, for example, a Sema3A neutralizing antibody, a Neuropilin-1 neutralizing antibody, or a soluble Neuropilin-1 or derivative thereof. Also disclosed is a method for screening a therapeutic agent for treating a cellular immune disease utilizing a signal generated by the interactions of Neuropilin-1, Plexin-A1 and Sema3A as a marker.
Public/Granted literature
- US20140349311A1 THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES OR ALLERGY, AND METHOD FOR SCREENING FOR THE THERAPEUTIC AGENT Public/Granted day:2014-11-27
Information query
IPC分类:
