Invention Grant
- Patent Title: Inhibitors of Rho/MRTF/SRF-mediated gene transcription and methods for use of the same
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Application No.: US16376349Application Date: 2019-04-05
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Publication No.: US10851072B2Publication Date: 2020-12-01
- Inventor: Scott D. Larsen , Richard Neubig , Kim Hutchings , Dylan Kahl , Erika Mathes Lisabeth
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN , BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
- Applicant Address: US MI Ann Arbor US MI East Lansing
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN,BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN,BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
- Current Assignee Address: US MI Ann Arbor US MI East Lansing
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C07D271/113
- IPC: C07D271/113 ; C07D271/06 ; C07D413/12 ; A61P35/00
Abstract:
Disclosed herein are inhibitors of Rho/MRTF/SRF-mediated gene transcription, and methods for their use in treating or preventing diseases such as cancer and fibrosis. In particular, disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof: wherein the substituents are as described.
Public/Granted literature
- US20190308947A1 INHIBITORS OF RHO/MRTF/SRF-MEDIATED GENE TRANSCRIPTION AND METHODS FOR USE OF THE SAME Public/Granted day:2019-10-10
Information query
