Invention Grant
- Patent Title: Bicyclic amines as novel JAK kinase inhibitors
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Application No.: US16479375Application Date: 2018-01-19
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Publication No.: US10851116B2Publication Date: 2020-12-01
- Inventor: Daniel Rodriguez Greve , Tue Heesgaard Jepsen , Mogens Larsen , Andreas Ritzen
- Applicant: LEO Pharma A/S
- Applicant Address: DK Ballerup
- Assignee: LEO Pharma A/S
- Current Assignee: LEO Pharma A/S
- Current Assignee Address: DK Ballerup
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: EP17152447 20170120
- International Application: PCT/EP2018/051305 WO 20180119
- International Announcement: WO2018/134352 WO 20180726
- Main IPC: C07D519/00
- IPC: C07D519/00 ; A61K31/519
Abstract:
The present invention relates to a compound according to formula I wherein R1 is alkyl; n is 1 or 2; R2 is selected from the group consisting of hydrogen, cyano, —SO2Ra, —SO2NRbRc, —C(O)Rb, phenyl and 5- and 6-membered heteroaryl or pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention relates further to pharmaceutical compositions comprising said compounds, and to methods of treating proliferative or inflammatory skin disorders with said compounds.
Public/Granted literature
- US20190382418A1 BICYCLIC AMINES AS NOVEL JAK KINASE INHIBITORS Public/Granted day:2019-12-19
Information query
