The invention relates to methods for preparing a three-dimensional digital model of a prosthetic denture base for fabrication using a light-based three-dimensional printing apparatus. A virtual reference model of a prosthetic denture base is prepared and manipulated to establish specific spatial orientation and angular inclination with respect to the build platform surface of the printing apparatus. Methods may include performing a corrective digital scaling process on the virtual reference model in order to achieve further improvements to dimensional accuracy in the fabrication of prosthetic denture bases.