Provided are a driving circuit and driving method for a display panel, and a display device. The driving method of a display panel includes that: the display panel includes a base substrate, a plurality of data lines and a plurality of scanlines; the plurality of data lines and the plurality of scanlines intersect to define a plurality of sub-pixels; each of pixel units is formed by adjacent N sub-pixels, a data line group is formed by every X data lines of the plurality of data lines connected to M columns of the pixel units, and the data line group is connected to a data signal output line through a multiplexer; the method further includes: controlling, through the multiplexer, data lines in a same data line group and corresponding to sub-pixels of a same color to continuously input data signals.