Multiple lookup tables (LUTs) storing different numbers of control point values are used to process pixels within different blocks of an image, such as after image processing using tone mapping and/or tone control, and/or to collect histogram information or implement 3D LUTs. First control point values stored within a first LUT are applied against pixels of a given block of an image to produce a distorted image block. Second control point values stored within a second lookup table are applied against a pixel of the distorted image block to produce a processed pixel. The second LUT is one of a plurality of second LUTs and stores fewer values than the first LUT. A processed image is produced using the processed pixel. The processed image is then output for further processing or display.