- 专利标题： Anti-Laminin4 antibodies specific for LG4-5
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申请号： US15918937申请日： 2018-03-12
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公开(公告)号： US10889636B2公开(公告)日： 2021-01-12
- 发明人: Stephen Jed Tam , Yue Liu , Robin Barbour , Theodore Yednock , Kenneth Flanagan
- 申请人： PROTHENA BIOSCIENCES LIMITED
- 申请人地址： IE County Dublin
- 专利权人： PROTHENA BIOSCIENCES LIMITED
- 当前专利权人： PROTHENA BIOSCIENCES LIMITED
- 当前专利权人地址： IE County Dublin
- 代理机构： Alston & Bird LLP
- 主分类号： A61K47/68
- IPC分类号： A61K47/68 ; C07K16/18 ; G01N33/574 ; A61K39/00
摘要：
The invention provides antibodies that specifically bind to the LG4-5 modules of the G domain of laminin α4. The antibodies can preferentially stain cancer or tumor cells or tissue. The antibodies can be used for detecting cancer, evaluating the efficacy of a cancer therapy, treating cancer, and treating obesity or obesity-related diseases, among other applications.
公开/授权文献
- US20180208646A1 ANTI-LAMININ4 ANTIBODIES SPECIFIC FOR LG4-5 公开/授权日：2018-07-26
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