- 专利标题: Method for detecting nucleosomes containing nucleotides
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申请号: US14239783申请日: 2012-08-31
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公开(公告)号: US10900064B2公开(公告)日: 2021-01-26
- 发明人: Jacob Vincent Micallef
- 申请人: Jacob Vincent Micallef
- 申请人地址: GB London
- 专利权人: Jacob Vincent Micallef
- 当前专利权人: Jacob Vincent Micallef
- 当前专利权人地址: GB London
- 代理机构: McDermott, Will & Emery LLP
- 代理商 Judy M. Mohr; Brett A. Schweers
- 优先权: GB1115095.0 20110901
- 国际申请: PCT/GB2012/052128 WO 20120831
- 国际公布: WO2013/030577 WO 20130307
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12Q1/6804 ; G01N33/58
摘要:
The invention relates to a method for detecting and measuring the presence of mono-nucleosomes and oligo-nucleosomes and nucleosomes that contain particular nucleotides and the use of such measurements for the detection and diagnosis of disease. The invention also relates to a method of identifying nucleosome associated nucleotide biomarkers for the detection and diagnosis of disease and to biomarkers identified by said method.
公开/授权文献
- US20140363812A1 METHOD FOR DETECTING NUCLEOSOMES CONTAINING NUCLEOTIDES 公开/授权日:2014-12-11
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