Autonomous ground vehicles (“AGVs”) receive items from transportation vehicles (e.g., delivery trucks) for delivery to specified locations. After the items are received, the AGVs may navigate along travel paths to delivery locations (e.g., at user residences) to deliver the items. The AGVs may include navigation systems and sensors (e.g., imaging sensors, distance detection sensors, etc.) to assist with the navigation, and may include locking mechanisms that lock the storage compartments of the AGVs while travelling.