A driving integrated circuit (IC) and a fan-out compensation method thereof are provided. The driving IC includes a plurality of driving channel circuits, a plurality of output buffer circuits and a compensation control circuit. The input terminals of the output buffer circuits are coupled to the output terminals of the driving channel circuits in a one-to-one manner. The output terminals of the output buffer circuits are coupled a plurality of data lines of a display panel in a one-to-one manner. The compensation control circuit is coupled to the output buffer circuits for adjusting the slew rate of the output terminals of the output buffer circuits to compensate difference in delay times between the data lines of the display panel.