Method for preparing methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylate
Abstract:
The invention relates to a method for preparing methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylate from 4-methoxycarbonyl-2-methylthiophene-3-sulfonyl chloride in the presence of an imidazole base substituted in the 1-position or in the presence of a mixture of bases comprising an imidazole base substituted in the 1-position (N-alkylimidazole).
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