Invention Grant
- Patent Title: Process for the preparation of tricyclic PI3K inhibitor compounds and methods for using the same for the treatment of cancer
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Application No.: US15780328Application Date: 2016-12-16
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Publication No.: US10906918B2Publication Date: 2021-02-02
- Inventor: Andreas Stumpf , Remy Angelaud , Andrew McClory , Herbert Yajima , Chudi Ndubaku , Alan Olivero
- Applicant: GENENTECH, INC.
- Applicant Address: US CA South San Francisco
- Assignee: GENENTECH, INC.
- Current Assignee: GENENTECH, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: K&L Gates LLP
- Agent Louis C. Cullman; Benjamin D. Heuberger
- International Application: PCT/US2016/067174 WO 20161216
- International Announcement: WO2017/106647 WO 20170622
- Main IPC: C07D498/14
- IPC: C07D498/14 ; C07D487/04 ; C07D498/22 ; A61P35/00 ; A61K9/00 ; A61K31/495 ; A61K31/5383 ; A61K39/395 ; A61K45/06
Abstract:
The present disclosure provides for methods for preparing tricyclic PI3K inhibitor compounds in high yield and purity in aqueous solvent systems.
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