A method and an apparatus for transmitting and receiving channel state information in a multi-antenna wireless communication system are disclosed. Specifically, a method for reporting channel state information (CSI), by a User Equipment (UE), in a multi-antenna wireless communication system, the method comprising receiving, from a base station, configuration information for single CSI reporting in which a non-precoded CSI-RS based CSI reporting and a beamformed CSI-RS based CSI reporting are combined, reporting a first Precoding Matrix Indicator (PMI) and/or a first Rank Indicator (RI) derived based on a non-precoded CSI-RS to the base station, and reporting a Channel Quality Indicator (CQI), a second PMI, and a second RI based on a beamformed CSI-RS to the base station, wherein a value of the first RI is determined as only a value belonging to a previously determined set.