Invention Grant
![Combinations comprising substituted imidazo[1,5-a]pyrazinones as PDE1 inhibitors](/docs/US/2021-02-09/US10912773B2/abs.jpg.600x600.jpg)
- Patent Title: Combinations comprising substituted imidazo[1,5-a]pyrazinones as PDE1 inhibitors
-
Application No.: US16345157Application Date: 2017-10-26
-
Publication No.: US10912773B2Publication Date: 2021-02-09
- Inventor: Jan Kehler , Lars Kyhn Rasmussen , Morten Langgård , Mikkel Jessing , Paulo Jorge Vieira Vital , Karsten Juhl
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: DK201600660 20161028
- International Application: PCT/EP2017/077503 WO 20171026
- International Announcement: WO2018/078042 WO 20180503
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; C07D487/04 ; A61P25/28 ; A61P25/16 ; A61K31/5377 ; A61K31/553 ; A61K45/06 ; A61K31/55
![Combinations comprising substituted imidazo[1,5-a]pyrazinones as PDE1 inhibitors](/abs-image/US/2021/02/09/US10912773B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides combination treatments comprising compounds of Formula (I): that are PDE1 enzyme inhibitors, and other compounds useful in the treatment of neurodegenerative disorders such as for example Alzheimer's Disease, Parkinson's Disease or Huntington's Disease. Separate aspects of the invention are directed to the combined use of said compounds for the treatment of neurodegenerative and/or cognitive disorders. The present invention also provides pharmaceutical compositions comprising said PDE1 enzyme inhibitors together with other compounds useful in the treatment of neurodegenerative disorders.
Public/Granted literature
- US20190282572A1 COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF IMIDAZOPYRAZINONES Public/Granted day:2019-09-19
Information query
IPC分类:
