Provided is a method of calculating permeability of a porous medium by using analysis of feature variables of friction flows through the porous medium for laminar and turbulent flows considering a geometric feature and a friction loss feature. A method of calculating permeability of a porous medium, according to an embodiment of the present invention, includes obtaining hydraulic diameters and friction factor-Reynolds number relationships of a plurality of reference porous media, deriving a hydraulic diameter-friction factor-Reynolds number correlation between the hydraulic diameters and the friction factor-Reynolds number relationships, and obtaining permeability of a porous medium to be predicted, by using the hydraulic diameter-friction factor-Reynolds number correlation.