Aspects of access devices and methods are disclosed. One aspect of this disclosure is a device. The device may comprise: a needle guide body extending along a central axis between a distal end and a proximal end, a needle guide lumen extending through the distal and proximal ends of the needle guide body along the central axis, and a base monolithically attached to the needle guide body to define a non-variable patient-specific insertion path. Additional devices and methods are disclosed.