Invention Grant
- Patent Title: Heterocyclic sulfones as ROR gamma modulators
-
Application No.: US16341474Application Date: 2017-10-12
-
Publication No.: US10934286B2Publication Date: 2021-03-02
- Inventor: Qingjie Liu , T. G. Murali Dhar , Lan-ying Qin , Lyndon A. M. Cornelius , Hai-Yun Xiao , Jianqing Li , Robert J. Cherney
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agent Elliott Korsen
- International Application: PCT/US2017/056257 WO 20171012
- International Announcement: WO2018/071620 WO 20180419
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D491/147

Abstract:
There are described RORγ modulators of the formula (I), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ Gamma activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ Gamma activity, for example, autoimmune and/or inflammatory disorders.
Public/Granted literature
- US20190300523A1 HETEROCYCLIC SULFONES AS ROR GAMMA MODULATORS Public/Granted day:2019-10-03
Information query