A method of detecting uncontrolled combustion in an internal combustion engine includes sampling in-cylinder pressure sensor configured to measure pressure in a cylinder of the engine and generate a pressure signal, calculating a combustion intensity metric based on the pressure signal, determining a parameter describing how close the engine is to an uncontrolled combustion condition based on the combustion intensity metric, and controlling a substitution rate of a first fuel and a second fuel based on one or more of the parameter and the combustion intensity metric.