Invention Grant
- Patent Title: AMPK-activating heterocyclic compounds and methods for using the same
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Application No.: US16451613Application Date: 2019-06-25
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Publication No.: US10941134B2Publication Date: 2021-03-09
- Inventor: Dane Goff , Donald Payan , Rajinder Singh , Simon Shaw , David Carroll , Yasumichi Hitoshi
- Applicant: Rigel Pharmaceuticals, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent James Diehl, Esq.
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D213/82 ; C07D401/06 ; C07D401/12 ; C07D405/14 ; C07D409/12 ; C07D409/14 ; C07D413/14 ; C07D417/14 ; C07D451/06 ; C07D471/10 ; C07D487/04 ; C07D495/04 ; C07D405/12 ; C07D213/81 ; C07D213/56 ; C07D401/04
Abstract:
Disclosed are substituted pyridine compounds as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure wherein E, J, T, the ring system denoted by “B”, T, R3, R4, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.
Public/Granted literature
- US20200017465A1 AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME Public/Granted day:2020-01-16
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