Invention Grant
- Patent Title: Hepatitis B antiviral agents
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Application No.: US16114842Application Date: 2018-08-28
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Publication No.: US10952978B2Publication Date: 2021-03-23
- Inventor: Yao-Ling Qiu , Xuri Gao , Jorden Kass , Hui Cao , Wei Li , Xiaowen Peng , Byung-Chul Suh , Yat Sun Or
- Applicant: ENANTA PHARMACEUTICALS, INC.
- Applicant Address: US MA Watertown
- Assignee: ENANTA PHARMACEUTICALS, INC.
- Current Assignee: ENANTA PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore
- Main IPC: A61K31/167
- IPC: A61K31/167 ; A61K31/4164 ; A61K31/34 ; A61K31/357 ; A61K31/4409 ; A61K31/426 ; A61K31/4015 ; A61K31/4439 ; A61K31/415 ; A61K31/421 ; A61K31/4192 ; A61K31/351 ; A61K31/397 ; A61K31/337 ; A61K31/47 ; A61K31/513 ; A61K31/7028 ; A61P31/20 ; A61K31/401 ; C07C303/00 ; C07C317/44 ; A61K45/06

Abstract:
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: X-A-Y-L-R (I) which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
Public/Granted literature
- US20190060258A1 HEPATITIS B ANTIVIRAL AGENTS Public/Granted day:2019-02-28
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