Invention Grant
- Patent Title: Macrocyclic compound and uses thereof
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Application No.: US16500924Application Date: 2018-04-03
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Publication No.: US10954249B2Publication Date: 2021-03-23
- Inventor: Yoshito Kishi , Kazunobu Kira , Ken Ito
- Applicant: President and Fellows of Harvard College , Eisai R&D Management Co., LTD.
- Applicant Address: US MA Cambridge; JP Tokyo
- Assignee: President and Fellows of Harvard College,Eisai R&D Management Co., LTD.
- Current Assignee: President and Fellows of Harvard College,Eisai R&D Management Co., LTD.
- Current Assignee Address: US MA Cambridge; JP Tokyo
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2018/025887 WO 20180403
- International Announcement: WO2018/187331 WO 20181011
- Main IPC: C07D493/22
- IPC: C07D493/22 ; A61K39/395 ; A61K31/357 ; C07K16/28 ; A61P35/00 ; A61K39/00
Abstract:
The present invention provides novel Compound (1) having tumor vascular remodeling effect and/or anti-CAF (Cancer Associated Fibroblasts) activity, or a pharmaceutically acceptable salt thereof, optionally in a pharmaceutically acceptable and medical uses thereof.
Public/Granted literature
- US20200148698A1 MACROCYCLIC COMPOUND AND USES THEREOF Public/Granted day:2020-05-14
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