- Patent Title: Stability-modulating linkers for use with antibody drug conjugates
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Application No.: US15504801Application Date: 2015-08-14
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Publication No.: US10967068B2Publication Date: 2021-04-06
- Inventor: Russell George Dushin , Pavel Strop , Magdalena Grazyna Dorywalska , Ludivine Moine
- Applicant: PFIZER INC. , RINAT NEUROSCIENCE CORP.
- Applicant Address: US NY New York; US CA South San Franciso
- Assignee: PFIZER INC.,RINAT NEUROSCIENCE CORP.
- Current Assignee: PFIZER INC.,RINAT NEUROSCIENCE CORP.
- Current Assignee Address: US NY New York; US CA South San Franciso
- Agency: Pfizer Inc.
- International Application: PCT/IB2015/056211 WO 20150814
- International Announcement: WO2016/030791 WO 20160303
- Main IPC: A61K47/65
- IPC: A61K47/65 ; A61K47/64 ; A61K47/68 ; A61K39/00
Abstract:
The present invention provides stability-modulated antibody-drug conjugates, stability-modulating linker components used to make these stability-modulated antibody-drug conjugates, therapeutic methods using stability-modulated antibody-drug conjugates, and methods of making stability modulating linkers and stability-modulated antibody-drug conjugates.
Public/Granted literature
- US20180140714A1 STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES Public/Granted day:2018-05-24
Information query
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