A circuit includes electrostatic discharge (ESD) protection circuitry, triggering circuitry, transient detection circuitry, and deactivation circuitry. The ESD protection circuitry is coupled between a first rail and a second rail. The triggering circuitry is configured to generate an ESD activation signal when a voltage across the first rail and the second rail exceeds a voltage threshold. The ESD protection circuitry is configured to activate based on the ESD activation signal. The transient detection circuitry is configured to generate a deactivation signal when the voltage across the first rail and the second rail comprises a voltage change over time that is less than a transient threshold. The deactivation circuitry is configured to deactivate the triggering circuitry based on the deactivation signal.