Systems including a resealable container and pre-moistened wipes packaged therein, the wipes including one or more characteristics correlated to desired properties, such as high durability, mileage, cleaning composition retention, efficacy, or the like are described. Pulp substrates typically include an anionic charge, which can result in binding or retention of a cationic biocide such as a quaternary ammonium compound while the remainder of the composition is released from the wipe (e.g., through squeezing, wiping or other compression). The present wipes may be specifically tailored to provide efficacy against Staphylococcus aureus population within 10 seconds to about 5 minutes, to include particular pore size distribution characteristics, and/or to include a mileage absorbency/desorbency factor (“MABDF”) value that is greater than 50. High MABDF values are indicative of good handfeel characteristics, improved more uniform dosing of composition loaded in the wipe, good microefficacy characteristics, and the like.