- 专利标题： Antibody conjugates comprising toll-like receptor agonist
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申请号： US15333285申请日： 2016-10-25
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公开(公告)号： US10973826B2公开(公告)日： 2021-04-13
- 发明人: Alex Cortez , Bernhard Hubert Geierstanger , Timothy Z. Hoffman , Shailaja Kasibhatla , Tetsuo Uno , Xing Wang , Tom Yao-Hsiang Wu
- 申请人： Alex Cortez , Bernhard Hubert Geierstanger , Timothy Z. Hoffman , Shailaja Kasibhatla , Tetsuo Uno , Xing Wang , Tom Yao-Hsiang Wu
- 申请人地址： US CA San Diego; US CA Solana Beach; US CA San Diego; US CA San Diego; US CA San Diego; US CA San Diego; US CA San Diego
- 专利权人： Alex Cortez,Bernhard Hubert Geierstanger,Timothy Z. Hoffman,Shailaja Kasibhatla,Tetsuo Uno,Xing Wang,Tom Yao-Hsiang Wu
- 当前专利权人： Alex Cortez,Bernhard Hubert Geierstanger,Timothy Z. Hoffman,Shailaja Kasibhatla,Tetsuo Uno,Xing Wang,Tom Yao-Hsiang Wu
- 当前专利权人地址： US CA San Diego; US CA Solana Beach; US CA San Diego; US CA San Diego; US CA San Diego; US CA San Diego; US CA San Diego
- 代理机构： Novartis Institutes for BioMedical Research, Inc.
- 代理商 Kun Wang
- 主分类号： A61K31/52
- IPC分类号： A61K31/52 ; A61K47/68 ; C07D487/04 ; C07H15/26 ; C07K16/28 ; C07K16/32
摘要：
Provided herein are antibody conjugates comprising toll-like receptor agonists and the use of such conjugates for the treatment of cancer. In some embodiments, the conjugates comprise anti-HER2 antibodies.
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