Invention Grant
- Patent Title: Antibodies to T cell immunoreceptor with IG and ITIM domains (TIGIT) and uses thereof
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Application No.: US16483870Application Date: 2019-02-11
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Publication No.: US10973853B2Publication Date: 2021-04-13
- Inventor: Feifei Cui , Lei Fang , Bingshi Guo , Zhengyi Wang , Jingwu Zang
- Applicant: I-Mab Biopharma US Limited
- Applicant Address: US MD Gaithersburg
- Assignee: I-Mab Biopharma US Limited
- Current Assignee: I-Mab Biopharma US Limited
- Current Assignee Address: US MD Gaithersburg
- Agency: Sheppard Mullin Richter & Hampton LLP
- Priority: WOPCT/CN2018/075477 20180206
- International Application: PCT/CN2019/074775 WO 20190211
- International Announcement: WO2019/154415 WO 20190815
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K35/17 ; A61P31/18 ; A61P35/00 ; C07K16/28

Abstract:
The present disclosure provides antibodies and fragments thereof having specificity to a human T cell immunoreceptor with Ig and ITIM domains (TIGIT) protein. Methods of using the antibodies or fragments thereof for treating and diagnosing diseases such as cancer and viral infections are also provided.
Public/Granted literature
- US20210015858A1 ANTIBODIES TO T CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS (TIGIT) AND USES THEREOF Public/Granted day:2021-01-21
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