发明授权
- 专利标题: High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
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申请号: US16463076申请日: 2017-11-24
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公开(公告)号: US10975060B2公开(公告)日: 2021-04-13
- 发明人: Markus Berger , Jessica Lohrke , Christoph-Stephan Hilger , Gregor Jost , Thomas Frenzel , Olaf Panknin , Hubertus Pietsch
- 申请人: BAYER PHARMA AKTIENGESELLSCHAFT
- 申请人地址: DE Berlin
- 专利权人: BAYER PHARMA AKTIENGESELLSCHAFT
- 当前专利权人: BAYER PHARMA AKTIENGESELLSCHAFT
- 当前专利权人地址: DE Berlin
- 代理商 Joseph L. Kent; David Schramm; James R Stevenson
- 优先权: EP16200932 20161128
- 国际申请: PCT/EP2017/080306 WO 20171124
- 国际公布: WO2018/096082 WO 20180531
- 主分类号: C07D403/14
- IPC分类号: C07D403/14 ; C07D257/02 ; A61K49/10
摘要:
The present invention relates to a new class of high relaxivity extracellular gadolinium chelate complexes, to methods of preparing said compounds, and to the use of said compounds as MRI contrast agents.
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