A display device capable of improving reliability (e.g., impact resistance) of a display panel having a through-hole, and a method of manufacturing a display device are provided. A display device includes: a camera module including a lens; a display panel including a through-hole overlapping the camera module on a plane; a window glass on the display panel; and a filling member in the through-hole and opposing each of the camera module and the window glass. A refractive index difference between an end portion of the filling member and the lens is about 0.7 or less, and a refractive index difference between another end portion of the filling member and the window glass is about 0.5 or less.