In example implementations, a method is provided that is executed by a processor. A multiplexed data stream is received over a single transmission control protocol (TCP) connection that uses a SPDY protocol. The multiplexed data stream contains data packets associated with a plurality of different data streams. A plurality of sub-contexts are generated. Each one of the sub-contexts is associated with a different one of the plurality of different data streams. The data packets are demultiplexed from the multiplexed data stream into a respective one of the plurality of sub-contexts. The plurality of different data streams in the respective one of the plurality of sub-contexts are examined to detect a malware.