Digital image layout training is described using wireframe rendering within a generative adversarial network (GAN) system. A GAN system is employed to train the generator module to refine digital image layouts. To do so, a wireframe rendering discriminator module rasterizes a refined digital training digital image layout received from a generator module into a wireframe digital image layout. The wireframe digital image layout is then compared with at least one ground truth digital image layout using a loss function as part of machine learning by the wireframe discriminator module. The generator module is then trained by backpropagating a result of the comparison.