In some embodiments, a plurality of real-time monitoring node signal inputs receive streams of monitoring node signal values over time that represent a current operation of the industrial asset control system. A threat detection computer platform, coupled to the plurality of real-time monitoring node signal inputs, may receive the streams of monitoring node signal values and, for each stream of monitoring node signal values, generate a current monitoring node feature vector. The threat detection computer platform may then compare each generated current monitoring node feature vector with a corresponding decision boundary for that monitoring node, the decision boundary separating a normal state from an abnormal state for that monitoring node, and localize an origin of a threat to a particular monitoring node. The threat detection computer platform may then automatically transmit a threat alert signal based on results of said comparisons along with an indication of the particular monitoring node.