Invention Grant
- Patent Title: Lipids and lipid compositions for the delivery of active agents
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Application No.: US16537934Application Date: 2019-08-12
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Publication No.: US11013696B2Publication Date: 2021-05-25
- Inventor: Luis Brito , Delai Chen , Gabriel Grant Gamber , Andrew Geall , Kevin Love , Thomas Zabawa , Frederic Zecri
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Brinks Gilson & Lione
- Main IPC: C07D319/06
- IPC: C07D319/06 ; C07C219/06 ; C07C229/12 ; C07D207/12 ; C07D207/16 ; C07D211/22 ; C07D211/62 ; C07C323/52 ; A61K31/7105 ; A61K31/713 ; C07C219/16 ; C07D233/60 ; C07D295/088 ; C12N15/88 ; A61K9/51 ; A61K9/127 ; A61K47/18 ; A61K38/18 ; A61K38/22 ; A61K39/12 ; C07C235/08 ; C07D211/06 ; C07D211/46 ; C07D233/64 ; C07D295/13 ; C12N7/00 ; C12N15/113 ; A61K39/00
Abstract:
This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1-R3, n, p, L1 and L2 are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.
Information query
