- 专利标题： Methods of treating insomnia using a combination therapy of low-dose doxepin and zolpidem
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申请号： US13612328申请日： 2012-09-12
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公开(公告)号： US11013712B2公开(公告)日： 2021-05-25
- 发明人: Philip Jochelson , Robert Mansbach , Michael Skinner , Neil B. Kavey
- 申请人： Philip Jochelson , Robert Mansbach , Michael Skinner , Neil B. Kavey
- 申请人地址： US CA San Diego; US CA San Diego; US CA San Diego; US NY Chappaqua
- 专利权人： Philip Jochelson,Robert Mansbach,Michael Skinner,Neil B. Kavey
- 当前专利权人： Philip Jochelson,Robert Mansbach,Michael Skinner,Neil B. Kavey
- 当前专利权人地址： US CA San Diego; US CA San Diego; US CA San Diego; US NY Chappaqua
- 代理机构： Servilla Whitney LLC
- 主分类号： A61K31/335
- IPC分类号： A61K31/335 ; A61K31/343 ; A61K31/4162 ; A61K31/437 ; A61K31/4535 ; A61K31/4985 ; A61K31/505 ; A61K31/55 ; A61K45/06 ; A61K9/20 ; A61K9/28 ; A61P25/00 ; A61P25/20
摘要：
A composition comprising doxepin, or a pharmaceutically acceptable salt, or prodrug thereof, and a compound that enhances sleep onset, sleep maintenance or reduces early morning awakenings. These compositions are useful for treating multiple manifestations of insomnia.