- Patent Title: Co-crystals of 1-(4-fluoro-phenyl)-4-((6bR,1OaS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H- pyrido[3′,4′:4,51_pyrrolo [1,2,3-delqcuinoxalin-8-yl)-butan-1-one with nicotinamide or isonicotinamide
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Application No.: US16090152Application Date: 2017-03-28
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Publication No.: US11014925B2Publication Date: 2021-05-25
- Inventor: Peng Li , Edwin Aret
- Applicant: INTRA-CELLULAR THERAPIES, INC.
- Applicant Address: US NY New York
- Assignee: INTRA-CELLULAR THERAPIES, INC.
- Current Assignee: INTRA-CELLULAR THERAPIES, INC.
- Current Assignee Address: US NY New York
- Agency: Hoxie & Associates LLC
- International Application: PCT/US2017/024597 WO 20170328
- International Announcement: WO2017/172811 WO 20171005
- Main IPC: C07D471/16
- IPC: C07D471/16 ; C07D213/82 ; A61K31/519 ; C07D213/81 ; A61K9/00 ; A61P25/18
Abstract:
The disclosure provides new, stable, pharmaceutically acceptable co-crystal forms of 1-(4-fluoro-phenyl)-4-((6bR, 10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8-yl)-butan-1-one, together with methods of making and using them, and pharmaceutical compositions comprising them.
Public/Granted literature
- US20200017500A9 NOVEL CO-CRYSTALS Public/Granted day:2020-01-16
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