An electronic device can include an integrated touch and display chip that can operate in multiple power domains. For example, the integrated touch and display chip can operate in a guarded power domain during the touch operation and can operate in a system power domain during non-guarded display operations. In some examples, two power domains can include a guarded power domain and a system power domain, whose grounds can be differentiated by a guard buffer signal. In some examples, the guard buffer can be disposed between the integrated touch and display chip and a battery of the device. In some examples, the guard buffer can be disposed between the battery of the device and the chassis of the device.