- 专利标题: Substituted N′-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase IDO inhibitors
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申请号: US16495883申请日: 2018-03-23
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公开(公告)号: US11034661B2公开(公告)日: 2021-06-15
- 发明人: Liangqin Guo , Yongxin Han , Kun Liu , Shuwen He , Joseph Kozlowski , Ravi Nargund , Wensheng Yu , Hongjun Zhang , Qinglin Pu , Derun Li , Abdelghani Achab , Guoqing Li
- 申请人: Merck Sharp & Dohme Corp. , Liangqin Guo , Yongxin Han , Kun Liu , Shuwen He , Joseph Kozlowski , Ravi Nargund , Wensheng Yu , Hongjun Zhang , Qinglin Pu , Derun Li , Abdelghani Achab , Guoqing Li
- 申请人地址: US NJ Rahway; US NJ Monroe Township; US MA Needham; US MA Needham; US NJ Fanwood; US NJ Princeton; US NJ East Brunswick; US NJ Edison; US MA Boston; US MA Needham; US MA Brighton; US MA Melrose; US NJ Belle Mead
- 专利权人: Merck Sharp & Dohme Corp.,Liangqin Guo,Yongxin Han,Kun Liu,Shuwen He,Joseph Kozlowski,Ravi Nargund,Wensheng Yu,Hongjun Zhang,Qinglin Pu,Derun Li,Abdelghani Achab,Guoqing Li
- 当前专利权人: Merck Sharp & Dohme Corp.,Liangqin Guo,Yongxin Han,Kun Liu,Shuwen He,Joseph Kozlowski,Ravi Nargund,Wensheng Yu,Hongjun Zhang,Qinglin Pu,Derun Li,Abdelghani Achab,Guoqing Li
- 当前专利权人地址: US NJ Rahway; US NJ Monroe Township; US MA Needham; US MA Needham; US NJ Fanwood; US NJ Princeton; US NJ East Brunswick; US NJ Edison; US MA Boston; US MA Needham; US MA Brighton; US MA Melrose; US NJ Belle Mead
- 代理商 Yong Zhao; Anna L. Cocuzzo
- 国际申请: PCT/US2018/023912 WO 20180323
- 国际公布: WO2018/183097 WO 20181004
- 主分类号: C07D271/08
- IPC分类号: C07D271/08 ; C07D413/12
摘要:
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof. Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.
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