- 专利标题： Sulphated disaccharides for the treatment of neuropathic pain
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申请号： US16499600申请日： 2018-03-06
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公开(公告)号： US11046722B2公开(公告)日： 2021-06-29
- 发明人: Josep Vergés Milano , Eulàlia Montell Bonaventura , Ramon Ruhí Roura , Carlos Raúl Aláez Versón , Antonio García García , Manuela García López , Juan Fernando Padín Nogueira , Marcos Maroto Pérez , Javier Egea Máiquez
- 申请人： BIOIBERICA, S.A.U. , UNIVERSIDAD AUTONOMA DE MADRID , FUNDACIÓN TEÓFILO HERNANDO
- 申请人地址： ES Palafolls; ES Madrid; ES Madrid
- 专利权人： BIOIBERICA, S.A.U.,UNIVERSIDAD AUTONOMA DE MADRID,FUNDACIÓN TEÓFILO HERNANDO
- 当前专利权人： BIOIBERICA, S.A.U.,UNIVERSIDAD AUTONOMA DE MADRID,FUNDACIÓN TEÓFILO HERNANDO
- 当前专利权人地址： ES Palafolls; ES Madrid; ES Madrid
- 代理机构： Hayes Soloway PC
- 优先权： ESES201730458 20170329
- 国际申请： PCT/EP2018/055430 WO 20180306
- 国际公布： WO2018/177693 WO 20181004
- 主分类号： C07H11/00
- IPC分类号： C07H11/00 ; A61P25/02
摘要：
The present invention relates to sulphated disaccharides of formula (I) for use in the treatment of neuropathic pain. The present invention also relates to a pharmaceutical composition comprising the compound of formula (I) and at least one pharmaceutically acceptable excipient for use in the treatment of neuropathic pain. The compounds of formula (I) were effective in several experimental models of neuropathic pain for which reason these compounds can be used effectively for the treatment of different types of neuropathic pain and the clinical manifestations thereof, for example, mechanical allodynia or cold allodynia.
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