- 专利标题: Coating composition, drug-containing particle, solid preparation and method for preparing drug-containing particle
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申请号: US14151205申请日: 2014-01-09
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公开(公告)号: US11052051B2公开(公告)日: 2021-07-06
- 发明人: Takuya Yokosawa , Yuichi Nishiyama , Naosuke Maruyama
- 申请人: Shin-Etsu Chemical Co., Ltd.
- 申请人地址: JP Tokyo
- 专利权人: Shin-Etsu Chemical Co., Ltd.
- 当前专利权人: Shin-Etsu Chemical Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Rimon, P.C.
- 优先权: JPJP2013-003534 20130111
- 主分类号: A61K9/50
- IPC分类号: A61K9/50 ; A61K9/00 ; A61K9/20 ; C09D101/32
摘要:
Provided are a drug-containing particle capable of suppressing dissolution of a drug in the oral cavity to suppress an unpleasant taste thereof and having excellent dissolution of the drug in the digestive tract after passing through the oral cavity; a method for preparing the drug-containing particle; a coating composition used for preparing the drug-containing particle; and a solid preparation having the drug-containing particle. More specifically, provided are a coating composition having 100 parts by weight of a cellulose-based enteric base and 50 parts by weight or less of a water-soluble cellulose ether; a drug-containing particle having a drug-containing core and a coat portion obtained by coating the core with the coating composition; a solid preparation having the drug-containing particle; and a method for preparing a drug-containing particle having a step of coating the drug-containing core with the coating composition.
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