Invention Grant
- Patent Title: Benzimidazole derivatives, preparation methods and uses thereof
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Application No.: US16471415Application Date: 2017-12-22
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Publication No.: US11053238B2Publication Date: 2021-07-06
- Inventor: Yiqian Wang , Jiabing Wang , Lieming Ding
- Applicant: BETTA PHARMACEUTICALS CO., LTD
- Applicant Address: CN Zhejiang
- Assignee: BETTA PHARMACEUTICALS CO., LTD
- Current Assignee: BETTA PHARMACEUTICALS CO., LTD
- Current Assignee Address: CN Zhejiang
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- Priority: WOPCT/CN2016/111457 20161222,WOPCT/CN2017/080661 20170414
- International Application: PCT/CN2017/117950 WO 20171222
- International Announcement: WO2018/113771 WO 20180628
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D487/04 ; C07D498/04 ; A61P35/04

Abstract:
The present invention relates to benzimidazole compounds useful in treating for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention of one or more symptoms of cancer, transplant rejections. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK4 and/or CDK6, using the compounds provided herein.
Public/Granted literature
- US20210130345A1 BENZIMIDAZOLE DERIVATIVES, PREPARATION METHODS AND USES THEREOF Public/Granted day:2021-05-06
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