The disclosure provides a method and a device in a User Equipment (UE) and a base station for wireless communication. In one embodiment, a first node performs first monitoring, determines, according to the first monitoring, that a first time-frequency resource pool is not available for a second-type transmission, and transmits first control information, the first control information being used for reserving the first time-frequency resource pool to a first-type transmission; wherein the first monitoring belongs to first-type monitoring; for the first-type transmission and the second-type transmission, second-type monitoring is only used for determining whether the first-type transmission can be performed; and the first-type monitoring is long-term while the second-type monitoring is short-term. The disclosure increases opportunities of transmission, thus improves efficiency of transmission and utilization of spectrum.