Invention Grant
- Patent Title: Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
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Application No.: US16578987Application Date: 2019-09-23
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Publication No.: US11084881B2Publication Date: 2021-08-10
- Inventor: Changyu Wang , Nils Lonberg , Alan J. Korman , Mark J. Selby , Mohan Srinivasan , Karla Henning , Michelle Minhua Han , Guodong Chen , Richard Huang , Indrani Chakraborty , Haichun Huang , Susan Wong , Huiming Li
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- Priority: WOPCT/US2015/033991 20150603
- Main IPC: C12N15/13
- IPC: C12N15/13 ; C07K16/28 ; A61K39/395 ; G01N33/68 ; G01N33/574 ; A61K39/00 ; A61K47/68
Abstract:
Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
Public/Granted literature
- US20200079865A1 ANTIBODIES AGAINST GLUCOCORTICOID-INDUCED TUMOR NECROSIS FACTOR RECEPTOR (GITR) AND USES THEREOF Public/Granted day:2020-03-12
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