A machining center configured for machining workpieces includes at least one column, a beam, at least one slider, a first driving member, a second driving member, a first main shaft and a second main shaft. The column can be configured for supporting the beam. The slider can be disposed on the beam and slidable along a length direction of the beam. Both the first main shaft and the second main shaft can be arranged on the slider and located on two opposite sides of the beam. The first driving member can be configured for driving the slider to slide relative to the beam. The second driving member can be configured for driving the first main shaft and the second main shaft to operate. The first main shaft and the second main shaft can be configured for synchronously or asynchronously machining the workpieces.