The present disclosure provides a capacitance compensation module, a capacitance compensation method, a self-capacitive touch display panel and a self-capacitive touch display device. The capacitance compensation module includes: a detection circuitry configured to detect an initial capacitance of a capacitor formed between each of the plurality of touch electrodes and the ground when the touch electrode is not being touched; a determination circuitry connected to the detection circuitry, and configured to determine whether the touch electrode is an abnormal touch electrode in accordance with the initial capacitance and output a compensation control signal when the touch electrode is the abnormal touch electrode; and a compensation circuitry connected to the determination circuitry and configured to, upon the receipt of the compensation control signal, apply a compensation voltage to the abnormal touch electrode, so as to enable the initial capacitance of the capacitor formed between the abnormal touch electrode and the ground to be within a standard capacitance range. According to at least one of embodiments of the present disclosure, it is able to at least partially prevent the occurrence of a capacitance warpage at a periphery of the self-capacitive touch display panel.