Various embodiments relate to analog-to-digital converter (ADC) controllers. An ADC controller may include a number of contexts configured for coupling to an ADC, wherein each context having at least one register for storing at least one configurable parameter. The ADC controller may also include a sequencer operatively coupled to the number of contexts and configured to perform a programmed conversion sequence based on one or more configurable parameters of one or more contexts of the number of contexts. Methods of performing an analog-to-digital (A/D) conversion sequence, and methods of configuring a number of contexts for an analog-to-digital converter (ADC) controller, are also disclosed.