- 专利标题： Pyridazinones and their use in the treatment of cancer
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申请号： US15750817申请日： 2016-08-05
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公开(公告)号： US11110089B2公开(公告)日： 2021-09-07
- 发明人: Elias Set Jenö Arnér , William Chester Stafford , Nathan Patrick Coussens , Diane Karen Luci , David Joseph Maloney , Anton Simeonov , Ajit Jadhav , Thomas S. Dexheimer
- 申请人： Elias Set Jenö Arnér , THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- 申请人地址： SE Stockholm; US MD Bethesda
- 专利权人： Elias Set Jenö Arnér,THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- 当前专利权人： Elias Set Jenö Arnér,THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- 当前专利权人地址： SE Stockholm; US MD Bethesda
- 代理机构： McCarter & English, LLP
- 代理商 Steven G. Davis; Mei Bai
- 优先权： GB1514015 20150807
- 国际申请： PCT/US2016/045729 WO 20160805
- 国际公布： WO2017/027357 WO 20170216
- 主分类号： C07D413/06
- IPC分类号： C07D413/06 ; A61K31/501 ; A61K45/06
摘要：
There is provided compounds of formula (I) or pharmaceutically-acceptable salts thereof, wherein W, X, Y, Z, R1, R2 and R3 have meanings provided in the description, which compounds are useful in the treatment of cancers.
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